Peptide reviews on one yardstick.
Every compound scored on the same five dimensions, published evidence, mechanism plausibility, human data, vendor trust, regulatory posture, and ranked. Last database refresh 2026-04-29.
The peptides you can actually buy, ranked.
Collagen peptide powders and peptide skincare, held to the same evidence yardstick as the research compounds. Rankings set by the ingredient panel and the published trials; commissions never reorder a list.
The best collagen peptides
Our pick: Momentous Grass-Fed Collagen
See the rankings
The best peptide serums
Our pick: The Ordinary Copper Peptides 1%
See the rankingsStart with the evidence: Collagen peptides, the evidence · Peptides in skincare · Copper peptides (GHK-Cu)
The research-peptide literature, ranked.
Nine compounds in active rotation, scored on a 10-point composite. Updated quarterly.
Top four on every dimension.
Higher is better. Numbers are tabular, the methodology is on the methodology page, and yes, vendor trust counts because counterfeit risk is real.
New reviews and evidence files.
Every post is graded against the published literature and dated, and we revise with a note when the file changes.
Collagen for osteoarthritis, what the evidence supports
Osteoarthritis breaks down cartilage, and collagen is that cartilage's main building block, so the question is fair. What the randomized trials show for hydrolyzed collagen and for undenatured type II collagen in knee osteoarthritis, whether cartilage itself changes, and where collagen sits alongside real OA care.
Peptides and inflammation, what the evidence supports
Several peptides calm inflammation in cell and animal models by mimicking the body's own regulatory signals. What the research shows for KPV, BPC-157, thymosin beta 4, and the melanocortins, how much of it has been tested in humans, and why none are approved anti-inflammatory treatments.
Collagen at menopause, what the evidence supports
Menopause accelerates collagen loss in skin and bone as estrogen falls. What supplemental collagen realistically does at this stage, where the randomized evidence is strongest, and why it is not a replacement for hormone therapy.
Collagen for bones, what the trials show
Collagen for bone health has one strong randomized trial behind it: 5 g of specific collagen peptides raised bone mineral density in postmenopausal women over a year. What the evidence shows, who it applies to, and where it does not replace osteoporosis treatment.
How to boost your own collagen production, by the evidence
How to boost collagen production on the evidence: the vitamin C and protein your body needs to build it, the topical retinoids that raise it, and the sun, smoking and sugar that break it down.
Collagen peptides versus collagen, what actually differs
Collagen peptides vs collagen on the evidence: why hydrolyzed peptides are absorbed while gelatin and whole collagen are not, which form the human trials actually used, and how undenatured type II fits.
Five shelves. Every review fits one.
Each shelf carries the reviews and the comparison tables for a single research domain.
Five dimensions, weighted, on every review.
Every score on Pepvise breaks down into the same five components. Read the full methodology if you want to argue with the weights, we will hear you out.
Read the full methodologySample size, replication count, and study design across PubMed, ClinicalTrials.gov, and FDA filings. Mouse-only literature gets capped.
Whether the proposed mechanism is consistent with established cell biology, or whether it is back-fitted to the marketing claim.
Trial phase, sample size, follow-up length, and the gap between rodent dose and the human dose actually studied.
Counterfeit incidence, third-party assay availability, regulatory posture of typical sources. Not an endorsement of any vendor.
FDA approval status, 503A/503B compoundability, WADA status, and the realistic legal pathway for a US patient or athlete.
On the pipeline.
Twelve reviews live, eight more in active drafting. Here is what is coming and when.
| Compound | Stage | Editor | Target pub |
|---|---|---|---|
| EpithalonEpitalon | Drafting | M. Otieno | 2026-06-12 |
| Thymosin α1 | Editor review | S. Han | 2026-06-19 |
| Selank | Pre-publication hold | M. Otieno | 2026-07-03 |
| Semax | Pre-publication hold | M. Otieno | 2026-07-10 |
One review a week. No vendor links. Ever.
When a new compound enters the database, or when an existing review gets a score change, subscribers hear about it first.
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